What it costs to vaccinate your dog in 25 cities

December 21, 2021 - 7 min read

Although it’s not quite from the moment they’re born, dogs are susceptible to a range of dangerous and fatal viruses shortly after birth. Like humans, female dogs provide passive immunity, or maternal immunity, to their puppies as protection against viruses even while they’re in utero. Most of the protective antibodies are passed on to puppies through their mother’s milk, but this only supports your dog’s immune system until they’re 12 weeks old. This is why it’s essential to schedule a series of vaccinations against diseases like Bordetella, canine distemper, parvovirus, leptospirosis, rabies, Lyme disease, and influenza for your puppy. These diseases can cause a wide range of harmful symptoms, including fever, lethargy, diarrhea, pain, and even death.

And, as a responsible pet owner, you must ensure their vaccinations are up-to-date annually. Just like us, dogs should complete a yearly visit with their vet, who will conduct a physical exam to check in on the animal’s health, recommend maintenance like dental cleaning, and administer vaccinations that have lapsed. (Adult dogs require regular booster vaccinations.) While the sum of a complete vaccination series can average $200, treatment of any of these diseases can cost thousands.

A study conducted by the University of California, Davis (published in 2014) found that dogs who contracted leptospirosis, which attacks the kidneys and liver, were hospitalized for an average of 11 days and racked up a treatment bill of more than $5,000. Treatment of parvovirus can cost up to $2,500. The fatality rate for dogs acquiring parvovirus who are unvaccinated, improperly vaccinated, or have lapsed vaccination is 90% when untreated. And without a rabies vaccination, dogs are susceptible to a viral disease that has no cure, can’t be treated with medication, and is essentially always fatal.

Where you live can impact exactly which vaccinations are recommended and how much they cost. For dogs living in a metro area like any of the 25 included on this list, their level of exposure to various diseases through boarding, dog parks, or dog walking services is greater than that of those living in more suburban or rural settings. For example, a vaccination against Bordetella—a highly contagious virus that causes kennel cough—is often required for dog services in cities.

Conversely, dogs that are more likely to pick up ticks, like those living near or frequently visiting wooded areas, are at a higher risk of contracting Lyme disease. Therefore, the Lyme disease vaccine should be a priority for these dogs, but not necessarily for those living in city centers, where fleas, heartworm disease, and intestinal parasites are often a larger concern than ticks. It’s important to consult with your dog’s veterinarian about which vaccine shots are required or recommended based on your location and lifestyle.

Operating a business in a metro area is often more expensive than operating that same business in a rural area due to higher overhead costs, so low cost vaccines are harder to come by. Veterinary practices and even vaccination clinics are no exception to this rule of real estate. These overhead costs are typically absorbed by you, the pet owner, who pays the bills for services like vaccination administration. Even within metro regions, costs can vary.

Data Source for Costs to Vaccinate Your Dog in 25 Cities

ManyPets used data from Banfield Pet Hospital’s price estimator tool to break down the cost of vaccinating your dog in the United States’ 25 most populous cities. The average cost mentioned refers to the average among the 25 most populous cities.

Here are our first five at a glance:

Vaccination NYC LA Chicago Houston Phoenix
Bordatella Vaccine $31.79 $32.57 $30.64 $29.18 $29.18
Distemper, Adenovirus, Parainfluenza, Parvo (DAPP) Vaccine $37.16 $38.07 $35.82 $34.11 $34.11
H3N2 and H3N8 Influenza Vaccine $50.31 $51.55 $48.50 $46.19 $46.19
Leptospirosis Vaccine $22.75 $23.31 $21.92 $20.88 $20.88
Lyme Disease Vaccine $40.82 $41.82 $39.34 $37.47 $37.47
Rabies Vaccine $26.40 $27.05 $25.45 $24.24 $24.24
Average Vaccination Cost $34.87 ($1.52 greater than average) $35.73 ($2.38 greater than average) $33.61 ($0.26 greater than average) $32.01 ($1.34 less than average) $32.01 ($1.34 less than average)

New York City dog

New York City

- Average vaccination cost: $34.87 ($1.52 more expensive than average)

--- Bordetella: $31.79

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $37.16

--- H3N2 and H3N8 influenza: $50.31

--- Leptospirosis: $22.75

--- Lyme disease: $40.82

--- Rabies: $26.40

Los Angeles

- Average vaccination cost: $35.73 ($2.38 more expensive than average)

--- Bordetella: $32.57

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $38.07

--- H3N2 and H3N8 influenza: $51.55

--- Leptospirosis: $23.31

--- Lyme disease: $41.82

--- Rabies: $27.05

Chicago

- Average vaccination cost: $33.61 ($0.26 more expensive than average)

--- Bordetella: $30.64

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $35.82

--- H3N2 and H3N8 influenza: $48.50

--- Leptospirosis: $21.92

--- Lyme disease: $39.34

--- Rabies: $25.45

Houston dog

Houston

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Phoenix dog

Phoenix

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Philadelphia dog

Philadelphia

- Average vaccination cost: $34.45 ($1.10 more expensive than average)

--- Bordetella: $31.40

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $36.70

--- H3N2 and H3N8 influenza: $49.70

--- Leptospirosis: $22.47

--- Lyme disease: $40.32

--- Rabies: $26.08

San Antonio dog

San Antonio

- Average vaccination cost: $31.63 ($1.72 less expensive than average)

--- Bordetella: $28.83

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $33.70

--- H3N2 and H3N8 influenza: $45.64

--- Leptospirosis: $20.63

--- Lyme disease: $37.02

--- Rabies: $23.95

San Diego dogs

San Diego

- Average vaccination cost: $36.16 ($2.81 more expensive than average)

--- Bordetella: $32.97

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $38.53

--- H3N2 and H3N8 influenza: $52.18

--- Leptospirosis: $23.59

--- Lyme disease: $42.33

--- Rabies: $27.38

Dallas dogs

Dallas

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Austin dog

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

San Jose dog

San Jose, California

- Average vaccination cost: $37.06 ($3.71 more expensive than average)

--- Bordetella: $33.78

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $39.49

--- H3N2 and H3N8 influenza: $53.47

--- Leptospirosis: $24.17

--- Lyme disease: $43.38

--- Rabies: $28.06

Fort Worth dog

Fort Worth, Texas

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Jacksonville dog

Jacksonville, Florida

- Average vaccination cost: $31.63 ($1.72 less expensive than average)

--- Bordetella: $28.83

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $33.70

--- H3N2 and H3N8 influenza: $45.64

--- Leptospirosis: $20.63

--- Lyme disease: $37.02

--- Rabies: $23.95

Columbus dog

Columbus, Ohio

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Charlotte dog

Charlotte, North Carolina

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Indianapolis dog

Indianapolis

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

San Francisco dog

San Francisco

- Average vaccination cost: $38.91 ($5.56 more expensive than average)

--- Bordetella: $35.47

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $41.46

--- H3N2 and H3N8 influenza: $56.14

--- Leptospirosis: $25.38

--- Lyme disease: $45.55

--- Rabies: $29.46

Seattle dog

Seattle

- Average vaccination cost: $34.87 ($1.52 more expensive than average)

--- Bordetella: $31.79

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $37.16

--- H3N2 and H3N8 influenza: $50.31

--- Leptospirosis: $22.75

--- Lyme disease: $40.82

--- Rabies: $26.40

Denver dog

Denver

- Average vaccination cost: $32.01 ($1.34 less expensive than average)

--- Bordetella: $29.18

---Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $34.11

--- H3N2 and H3N8 influenza: $46.19

--- Leptospirosis: $20.88

--- Lyme disease: $37.47

--- Rabies: $24.24

Washington DC dog

District of Columbia

- Average vaccination cost: $34.87 ($1.52 more expensive than average)

--- Bordetella: $31.79

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $37.16

--- H3N2 and H3N8 influenza: $50.31

--- Leptospirosis: $22.75

--- Lyme disease: $40.82

--- Rabies: $26.40

Boston dogs

Boston

- Average vaccination cost: $34.87 ($1.52 more expensive than average)

--- Bordetella: $31.79

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $37.16

--- H3N2 and H3N8 influenza: $50.31

--- Leptospirosis: $22.75

--- Lyme disease: $40.82

--- Rabies: $26.40

El Paso dog

El Paso, Texas

- Average vaccination cost: $30.87 ($2.48 less expensive than average)

--- Bordetella: $28.14

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $32.89

--- H3N2 and H3N8 influenza: $44.54

--- Leptospirosis: $20.14

--- Lyme disease: $36.13

--- Rabies: $23.38

Nashville dog

Nashville, Tennessee

- Average vaccination cost: $31.24 ($2.11 less expensive than average)

--- Bordetella: $28.48

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $33.29

--- H3N2 and H3N8 influenza: $45.08

--- Leptospirosis: $20.38

--- Lyme disease: $36.57

--- Rabies: $23.66

Oklahoma City dog

Oklahoma City

- Average vaccination cost: $31.24 ($2.11 less expensive than average)

--- Bordetella: $28.48

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $33.29

--- H3N2 and H3N8 influenza: $45.08

--- Leptospirosis: $20.38

--- Lyme disease: $36.57

--- Rabies: $23.66

Las Vegas dog

Las Vegas

- Average vaccination cost: $33.61 ($0.26 more expensive than average)

--- Bordetella: $30.64

--- Distemper, Adenovirus, Parainfluenza, Parvo (DAPP): $35.82

--- H3N2 and H3N8 influenza: $48.50

--- Leptospirosis: $21.92

--- Lyme disease: $39.34

--- Rabies: $25.45


Lauren Liebhaber is a Senior Staff Writer for Stacker with a passion for covering breaking news, current events, and local journalism. She attended the S.I. Newhouse School Of Public Communications at Syracuse University for graduate school.